| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
|---|
| Ligand | BDBM50348122 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_757136 (CHEMBL1803276) |
|---|
| Ki | >20000±n/a nM |
|---|
| Citation |  Watson, C; Owen, DR; Harding, D; Kon-I, K; Lewis, ML; Mason, HJ; Matsumizu, M; Mukaiyama, T; Rodriguez-Lens, M; Shima, A; Takeuchi, M; Tran, I; Young, T Optimisation of a novel series of selective CNS penetrant CB(2) agonists. Bioorg Med Chem Lett21:4284-7 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cannabinoid receptor 1 |
|---|
| Name: | Cannabinoid receptor 1 |
|---|
| Synonyms: | CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 52868.96 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P21554 |
|---|
| Residue: | 472 |
|---|
| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
|
|
|
|---|
| BDBM50348122 |
|---|
| n/a |
|---|
| Name | BDBM50348122 |
|---|
| Synonyms: | CHEMBL1800168 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H24N2O2S |
|---|
| Mol. Mass. | 320.45 |
|---|
| SMILES | CCS(=O)(=O)c1ccc2n(CC3CC3)c(nc2c1)C(C)(C)C |
|---|
| Structure | 
|
|---|
Search and Browse
