| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50348130 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_757135 (CHEMBL1803275) |
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| EC50 | 11±n/a nM |
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| Citation |  Watson, C; Owen, DR; Harding, D; Kon-I, K; Lewis, ML; Mason, HJ; Matsumizu, M; Mukaiyama, T; Rodriguez-Lens, M; Shima, A; Takeuchi, M; Tran, I; Young, T Optimisation of a novel series of selective CNS penetrant CB(2) agonists. Bioorg Med Chem Lett21:4284-7 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50348130 |
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| n/a |
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| Name | BDBM50348130 |
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| Synonyms: | CHEMBL1800177 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H26N2O3S |
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| Mol. Mass. | 350.476 |
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| SMILES | CCS(=O)(=O)c1ccc2n(C[C@@H]3CCCO3)c(nc2c1)C(C)(C)C |r| |
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| Structure | 
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