| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50348154 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_757185 (CHEMBL1803409) |
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| Ki | 1.46±n/a nM |
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| Citation |  Baraldi, PG; Preti, D; Zaid, AN; Saponaro, G; Tabrizi, MA; Baraldi, S; Romagnoli, R; Moorman, AR; Varani, K; Cosconati, S; Di Maro, S; Marinelli, L; Novellino, E; Borea, PA New 2-heterocyclyl-imidazo[2,1-i]purin-5-one derivatives as potent and selective human A3 adenosine receptor antagonists. J Med Chem54:5205-20 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50348154 |
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| n/a |
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| Name | BDBM50348154 |
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| Synonyms: | CHEMBL1800783 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21N7O2 |
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| Mol. Mass. | 355.3943 |
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| SMILES | CC[C@@H]1Cn2c(N1)c1nc(nc1n(CC=C)c2=O)-c1cc(OC)nn1C |r| |
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| Structure | 
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