| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide S receptor |
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| Ligand | BDBM50348587 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_755375 (CHEMBL1804531) |
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| IC50 | 369±n/a nM |
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| Citation |  Trotter, BW; Nanda, KK; Manley, PJ; Uebele, VN; Condra, CL; Gotter, AL; Menzel, K; Henault, M; Stocco, R; Renger, JJ; Hartman, GD; Bilodeau, MT Tricyclic imidazole antagonists of the Neuropeptide S Receptor. Bioorg Med Chem Lett20:4704-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide S receptor |
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| Name: | Neuropeptide S receptor |
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| Synonyms: | GPR154 | GPRA | NPSR1 | NPSR1_HUMAN | PGR14 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 42692.30 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1276607 |
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| Residue: | 371 |
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| Sequence: | MPANFTEGSFDSSGTGQTLDSSPVACTETVTFTEVVEGKEWGSFYYSFKTEQLITLWVLF
VFTIVGNSVVLFSTWRRKKKSRMTFFVTQLAITDSFTGLVNILTDINWRFTGDFTAPDLV
CRVVRYLQVVLLYASTYVLVSLSIDRYHAIVYPMKFLQGEKQARVLIVIAWSLSFLFSIP
TLIIFGKRTLSNGEVQCWALWPDDSYWTPYMTIVAFLVYFIPLTIISIMYGIVIRTIWIK
SKTYETVISNCSDGKLCSSYNRGLISKAKIKAIKYSIIIILAFICCWSPYFLFDILDNFN
LLPDTQERFYASVIIQNLPALNSAINPLIYCVFSSSISFPCREQRSQDSRMTFRERTERH
EMQILSKPEFI
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| BDBM50348587 |
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| n/a |
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| Name | BDBM50348587 |
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| Synonyms: | CHEMBL1801268 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H16BrN3 |
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| Mol. Mass. | 426.308 |
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| SMILES | Brc1ccc(cc1)C1(Cc2ccccc2C#N)c2ccccc2-c2nccn12 |
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| Structure | 
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