| Reaction Details |
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 | Report a problem with these data |
| Target | Thromboxane A2 receptor |
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| Ligand | BDBM50348614 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_755468 (CHEMBL1804937) |
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| IC50 | 7000±n/a nM |
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| Citation |  Trotter, BW; Nanda, KK; Manley, PJ; Uebele, VN; Condra, CL; Gotter, AL; Menzel, K; Henault, M; Stocco, R; Renger, JJ; Hartman, GD; Bilodeau, MT Tricyclic imidazole antagonists of the Neuropeptide S Receptor. Bioorg Med Chem Lett20:4704-8 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Thromboxane A2 receptor |
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| Name: | Thromboxane A2 receptor |
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| Synonyms: | Prostanoid TP receptor | TA2R_HUMAN | TBXA2R | TXA2-R | Thromboxane | Thromboxane A2 receptor | Thromboxane Beta |
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| Type: | Enyzme |
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| Mol. Mass.: | 37445.28 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P21731 |
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| Residue: | 343 |
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| Sequence: | MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
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| BDBM50348614 |
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| n/a |
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| Name | BDBM50348614 |
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| Synonyms: | CHEMBL1801358 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H23ClN2O2 |
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| Mol. Mass. | 394.894 |
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| SMILES | COc1ccc-2c(c1)C(CC1CCOCC1)(c1ccc(Cl)cc1)n1ccnc-21 |
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| Structure | 
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