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TargetMu-type opioid receptor
LigandBDBM50348871
Substrate/Competitorn/a
Meas. Tech.ChEMBL_757805 (CHEMBL1809749)
Ki 250±n/a nM
Citation Li, FFolk, JECheng, KKurimura, MDeck, JADeschamps, JRRothman, RBDersch, CMJacobson, AERice, KC Probes for narcotic receptor mediated phenomena. 43. Synthesis of the ortho-a and para-a, and improved synthesis and optical resolution of the ortho-b and para-b oxide-bridged phenylmorphans: compounds with moderate to low opioid-receptor affinity. Bioorg Med Chem19:4330-7 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Mu-type opioid receptor
Name:Mu-type opioid receptor
Synonyms:M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:44789.51
Organism:Homo sapiens (Human)
Description:P35372
Residue:400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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  Blast E-value cutoff:
BDBM50348871
n/a
NameBDBM50348871
Synonyms:CHEMBL1808303
TypeSmall organic molecule
Emp. Form.C22H25NO2
Mol. Mass.335.4394
SMILESOc1ccc2O[C@H]3CC[C@@H]4C[C@]3(CCN4CCc3ccccc3)c2c1 |r|
Structure
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