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TargetPeptide deformylase mitochondrial
LigandBDBM50349077
Substrate/Competitorn/a
Meas. Tech.ChEMBL_759151
IC50 45000±n/a nM
Citation Antczak CShum DBassit BFrattini MGLi Yde Stanchina EScheinberg DADjaballah H Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase. Bioorg Med Chem Lett 21:4528-32 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peptide deformylase mitochondrial
Name:Peptide deformylase mitochondrial
Synonyms:Peptide deformylase, mitochondrial | Polypeptide deformylase
Type:PROTEIN
Mol. Mass.:27023.25
Organism:Homo sapiens (Human)
Description:ChEMBL_154318
Residue:243
Sequence:
MARLWGALSLWPLWAAVPWGGAAAVGVRACSSTAAPDGVEGPALRRSYWRHLRRLVLGPP
EPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVGLSAPQLGVPR
QVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLA
CVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSRTFTNVYWMK
VND
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BDBM50349077
n/a
NameBDBM50349077
Synonyms:CHEMBL1807949
TypeSmall organic molecule
Emp. Form.C15H6Cl2O4
Mol. Mass.321.112
SMILESClC1=C(Cl)C(=O)C(=O)c2c(coc12)C(=O)c1ccccc1 |c:1|
Structure
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