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TargetPeptide deformylase, mitochondrial
LigandBDBM50349087
Substrate/Competitorn/a
Meas. Tech.ChEMBL_759151 (CHEMBL1811208)
IC50 10000±n/a nM
Citation Antczak, CShum, DBassit, BFrattini, MGLi, Yde Stanchina, EScheinberg, DADjaballah, H Identification of benzofuran-4,5-diones as novel and selective non-hydroxamic acid, non-peptidomimetic based inhibitors of human peptide deformylase. Bioorg Med Chem Lett21:4528-32 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Peptide deformylase, mitochondrial
Name:Peptide deformylase, mitochondrial
Synonyms:DEFM_HUMAN | PDF | PDF1A | Peptide deformylase mitochondrial | Peptide deformylase, mitochondrial | Polypeptide deformylase
Type:PROTEIN
Mol. Mass.:27023.25
Organism:Homo sapiens (Human)
Description:ChEMBL_154318
Residue:243
Sequence:
MARLWGALSLWPLWAAVPWGGAAAVGVRACSSTAAPDGVEGPALRRSYWRHLRRLVLGPP
EPPFSHVCQVGDPVLRGVAAPVERAQLGGPELQRLTQRLVQVMRRRRCVGLSAPQLGVPR
QVLALELPEALCRECPPRQRALRQMEPFPLRVFVNPSLRVLDSRLVTFPEGCESVAGFLA
CVPRFQAVQISGLDPNGEQVVWQASGWAARIIQHEMDHLQGCLFIDKMDSRTFTNVYWMK
VND
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  Blast E-value cutoff:
BDBM50349087
n/a
NameBDBM50349087
Synonyms:CHEMBL1807999
TypeSmall organic molecule
Emp. Form.C17H10Br2O6
Mol. Mass.470.066
SMILESCOc1ccc(cc1OC)C(=O)c1coc2c1C(=O)C(=O)C(Br)=C2Br |c:24|
Structure
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