| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cathepsin G |
|---|
| Ligand | BDBM50349177 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_759675 (CHEMBL1811508) |
|---|
| IC50 | >10±n/a nM |
|---|
| Citation |  Lo, HY; Nemoto, PA; Kim, JM; Hao, MH; Qian, KC; Farrow, NA; Albaugh, DR; Fowler, DM; Schneiderman, RD; Michael August, E; Martin, L; Hill-Drzewi, M; Pullen, SS; Takahashi, H; De Lombaert, S Benzimidazolone as potent chymase inhibitor: modulation of reactive metabolite formation in the hydrophobic (P1) region. Bioorg Med Chem Lett21:4533-9 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cathepsin G |
|---|
| Name: | Cathepsin G |
|---|
| Synonyms: | CATG_HUMAN | CG | CTSG |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 28860.08 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1469016 |
|---|
| Residue: | 255 |
|---|
| Sequence: | MQPLLLLLAFLLPTGAEAGEIIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVL
TAAHCWGSNINVTLGAHNIQRRENTQQHITARRAIRHPQYNQRTIQNDIMLLQLSRRVRR
NRNVNPVALPRAQEGLRPGTLCTVAGWGRVSMRRGTDTLREVQLRVQRDRQCLRIFGSYD
PRRQICVGDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSSGVPPEVFTRVSSFLPWIRT
TMRSFKLLDQMETPL
|
|
|
|---|
| BDBM50349177 |
|---|
| n/a |
|---|
| Name | BDBM50349177 |
|---|
| Synonyms: | CHEMBL1807639 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H25N3O4 |
|---|
| Mol. Mass. | 407.4623 |
|---|
| SMILES | COc1cc(Cn2c3ccccc3n(CCC(O)=O)c2=O)c2n(C)c(C)c(C)c2c1 |
|---|
| Structure | 
|
|---|
Search and Browse
