| Reaction Details |
|---|
 | Report a problem with these data |
| Target | 3-oxoacyl-[acyl-carrier-protein] synthase 3 |
|---|
| Ligand | BDBM50349316 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_760083 (CHEMBL1810406) |
|---|
| Ki | 0.002730±n/a nM |
|---|
| Citation |  Zhang, HJ; Zhu, DD; Li, ZL; Sun, J; Zhu, HL Synthesis, molecular modeling and biological evaluation ofß-ketoacyl-acyl carrier protein synthase III (FabH) as novel antibacterial agents. Bioorg Med Chem19:4513-9 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| 3-oxoacyl-[acyl-carrier-protein] synthase 3 |
|---|
| Name: | 3-oxoacyl-[acyl-carrier-protein] synthase 3 |
|---|
| Synonyms: | 3-oxoacyl-[acyl-carrier-protein] synthase | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | 3-oxoacyl-[acyl-carrier-protein] synthase III | Beta-ketoacyl-ACP synthase III (FabH) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 33506.68 |
|---|
| Organism: | Escherichia coli |
|---|
| Description: | C3TDZ2 |
|---|
| Residue: | 317 |
|---|
| Sequence: | MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHIAAPNETVSTMGFEAAT
RAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKGCPAFDVAAACAGFTYALS
VADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDGAGAAVLAASEEPGIISTHLH
ADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVTELAHIVDETLAANNLDRSQLDW
LVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTSAASVPCALDEAVRDGRIKPGQLVL
LEAFGGGFTWGSALVRF
|
|
|
|---|
| BDBM50349316 |
|---|
| n/a |
|---|
| Name | BDBM50349316 |
|---|
| Synonyms: | CHEMBL1807928 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H19N3O5 |
|---|
| Mol. Mass. | 345.3499 |
|---|
| SMILES | COc1cccc(\C=C\C(=O)OC(C)Cn2c(C)ncc2[N+]([O-])=O)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
