| Reaction Details |
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 | Report a problem with these data |
| Target | 3-oxoacyl-[acyl-carrier-protein] synthase 3 |
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| Ligand | BDBM50349329 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_760083 (CHEMBL1810406) |
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| Ki | 0.000443440±n/a nM |
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| Citation |  Zhang, HJ; Zhu, DD; Li, ZL; Sun, J; Zhu, HL Synthesis, molecular modeling and biological evaluation ofß-ketoacyl-acyl carrier protein synthase III (FabH) as novel antibacterial agents. Bioorg Med Chem19:4513-9 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 3-oxoacyl-[acyl-carrier-protein] synthase 3 |
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| Name: | 3-oxoacyl-[acyl-carrier-protein] synthase 3 |
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| Synonyms: | 3-oxoacyl-[acyl-carrier-protein] synthase | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | 3-oxoacyl-[acyl-carrier-protein] synthase III | Beta-ketoacyl-ACP synthase III (FabH) |
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| Type: | Enzyme |
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| Mol. Mass.: | 33506.68 |
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| Organism: | Escherichia coli |
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| Description: | C3TDZ2 |
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| Residue: | 317 |
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| Sequence: | MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHIAAPNETVSTMGFEAAT
RAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKGCPAFDVAAACAGFTYALS
VADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDGAGAAVLAASEEPGIISTHLH
ADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVTELAHIVDETLAANNLDRSQLDW
LVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTSAASVPCALDEAVRDGRIKPGQLVL
LEAFGGGFTWGSALVRF
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| BDBM50349329 |
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| n/a |
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| Name | BDBM50349329 |
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| Synonyms: | CHEMBL1807661 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H19N3O4 |
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| Mol. Mass. | 365.3826 |
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| SMILES | CC(Cn1c(C)ncc1[N+]([O-])=O)OC(=O)\C=C\c1cccc2ccccc12 |
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| Structure | 
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