| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transmembrane protease serine 11D |
|---|
| Ligand | BDBM50349364 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_760105 (CHEMBL1810428) |
|---|
| Ki | 76±n/a nM |
|---|
| Citation |  Sielaff, F; Böttcher-Friebertshäuser, E; Meyer, D; Saupe, SM; Volk, IM; Garten, W; Steinmetzer, T Development of substrate analogue inhibitors for the human airway trypsin-like protease HAT. Bioorg Med Chem Lett21:4860-4 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Transmembrane protease serine 11D |
|---|
| Name: | Transmembrane protease serine 11D |
|---|
| Synonyms: | Airway trypsin-like protease | HAT | TM11D_HUMAN | TMPRSS11D | Transmembrane protease serine 11D catalytic chain | Transmembrane protease serine 11D non-catalytic chain |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 46272.53 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_840134 |
|---|
| Residue: | 418 |
|---|
| Sequence: | MYRPARVTSTSRFLNPYVVCFIVVAGVVILAVTIALLVYFLAFDQKSYFYRSSFQLLNVE
YNSQLNSPATQEYRTLSGRIESLITKTFKESNLRNQFIRAHVAKLRQDGSGVRADVVMKF
QFTRNNNGASMKSRIESVLRQMLNNSGNLEINPSTEITSLTDQAAANWLINECGAGPDLI
TLSEQRILGGTEAEEGSWPWQVSLRLNNAHHCGGSLINNMWILTAAHCFRSNSNPRDWIA
TSGISTTFPKLRMRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNI
PPGSTAYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGG
VDACQGDSGGPLVQEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQQTGI
|
|
|
|---|
| BDBM50349364 |
|---|
| n/a |
|---|
| Name | BDBM50349364 |
|---|
| Synonyms: | CHEMBL1809219 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H33N5O4S |
|---|
| Mol. Mass. | 499.626 |
|---|
| SMILES | CC(C)[C@@H](NS(=O)(=O)Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)NCc1ccc(cc1)C(N)=N |r| |
|---|
| Structure | 
|
|---|
Search and Browse
