| Reaction Details |
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 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
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| Ligand | BDBM50349676 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_760041 (CHEMBL1810317) |
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| IC50 | 23±n/a nM |
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| Citation |  Thoma, G; Baenteli, R; Lewis, I; Jones, D; Kovarik, J; Streiff, MB; Zerwes, HG Special ergolines efficiently inhibit the chemokine receptor CXCR3 in blood. Bioorg Med Chem Lett21:4745-9 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-X-C chemokine receptor type 3 |
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| Name: | C-X-C chemokine receptor type 3 |
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| Synonyms: | CXCR3_RAT | Cxcr3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 40937.37 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_760041 |
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| Residue: | 367 |
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| Sequence: | MYLEVSERQVLDASDIAFLLENSTSPYDYGENESDFSDSPPCPQDFSLNFDRTFLPVLYS
LLFLLGLLGNGAVAAVLLSQRTALSSTDTFLLHLAVADVLLVLTLPLWAVDAAAQWVFGS
GLCKVAGALFNINFYAGAFLLACISFDRYLSIVHATQIYRRDPWVRVALTCIVVWGLCVL
FALPDFIFLSASHDQRLNATHCQYNFPQVGRTALRVLQLVAGFLMPLLVMAYCYAHILAV
LLVSRGQRRFRAMRLVVVVVVAFAVCWTPYHLVVLVDILMDVGVLARNCGRESHVDVAKS
VTSGMGYMHCCLNPLLYAFVGVKFKEQMWMLLMRLGRSDQRGPQRQPSSSRRESSWSETT
EASYLGL
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| BDBM50349676 |
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| n/a |
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| Name | BDBM50349676 |
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| Synonyms: | CHEMBL1809042 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H40N6O2 |
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| Mol. Mass. | 552.7097 |
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| SMILES | CN1CCN(CCn2cc3C[C@H]4N(C[C@@H](C=C4c4cccc2c34)C(=O)N2CCCC2)C(=O)Nc2ccccc2)CC1 |r,c:15| |
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| Structure | 
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