| Reaction Details |
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 | Report a problem with these data |
| Target | Kappa-type opioid receptor |
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| Ligand | BDBM50350091 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_760921 (CHEMBL1814859) |
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| IC50 | 32400±n/a nM |
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| Citation |  Gao, J; León, F; Radwan, MM; Dale, OR; Husni, AS; Manly, SP; Lupien, S; Wang, X; Hill, RA; Dugan, FM; Cutler, HG; Cutler, SJ Benzyl derivatives with in vitro binding affinity for human opioid and cannabinoid receptors from the fungus Eurotium repens. J Nat Prod74:1636-9 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Kappa-type opioid receptor |
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| Name: | Kappa-type opioid receptor |
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| Synonyms: | K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 42648.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P41145 |
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| Residue: | 380 |
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| Sequence: | MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPV
IITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYL
MNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINI
CIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVL
IIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALG
STSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRV
RNTVQDPAYLRDIDGMNKPV
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| BDBM50350091 |
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| n/a |
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| Name | BDBM50350091 |
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| Synonyms: | CHEMBL1813663 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H28O3 |
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| Mol. Mass. | 316.4345 |
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| SMILES | [#6]-[#6]-[#6]-[#6]-[#6]\[#6]=[#6]\c1c2-[#6]-[#6](-[#8])-[#8]-c2c(-[#6]\[#6]=[#6](\[#6])-[#6])cc1-[#8] |
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| Structure | 
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