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TargetArginase-1
LigandBDBM50350309
Substrate/Competitorn/a
Meas. Tech.ChEMBL_762137
Kd 8.8E2±n/a nM
Citation Ilies MDi Costanzo LDowling DPThorn KJChristianson DW Binding ofa,a-disubstituted amino acids to arginase suggests new avenues for inhibitor design. J Med Chem 54:5432-43 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Arginase-1
Name:Arginase-1
Synonyms:ARG1 | Liver-type arginase | Type I arginase
Type:PROTEIN
Mol. Mass.:34737.53
Organism:Homo sapiens (Human)
Description:ChEMBL_978893
Residue:322
Sequence:
MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
LACFGLAREGNHKPIDYLNPPK
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  Blast E-value cutoff:
BDBM50350309
n/a
NameBDBM50350309
Synonyms:CHEMBL1812662
TypeSmall organic molecule
Emp. Form.C7H16BNO4
Mol. Mass.189.017
SMILESCC([NH3+])(CCCCB(O)O)C([O-])=O
Structure
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