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TargetArginase-2, mitochondrial
LigandBDBM50350311
Substrate/Competitorn/a
Meas. Tech.ChEMBL_762135
Ki 8.5±n/a nM
Citation Ilies MDi Costanzo LDowling DPThorn KJChristianson DW Binding ofa,a-disubstituted amino acids to arginase suggests new avenues for inhibitor design. J Med Chem 54:5432-43 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Arginase-2, mitochondrial
Name:Arginase-2, mitochondrial
Synonyms:ARG2 | Arginase II | Kidney-type arginase | Non-hepatic arginase | Type II arginase
Type:PROTEIN
Mol. Mass.:38576.93
Organism:Homo sapiens (Human)
Description:ChEMBL_978892
Residue:354
Sequence:
MSLRGSLSRLLQTRVHSILKKSVHSVAVIGAPFSQGQKRKGVEHGPAAIREAGLMKRLSS
LGCHLKDFGDLSFTPVPKDDLYNNLIVNPRSVGLANQELAEVVSRAVSDGYSCVTLGGDH
SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG
FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG
KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ
LATSEEEAKTTANLAVDVIASSFGQTREGGHIVYDQLPTPSSPDESENQARVRI
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  Blast E-value cutoff:
BDBM50350311
n/a
NameBDBM50350311
Synonyms:CHEMBL1812661
TypeSmall organic molecule
Emp. Form.C6H14BNO4
Mol. Mass.174.991
SMILES[NH3+][C@@H](CCCCB(O)O)C([O-])=O |r|
Structure
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