| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Arginase-1 |
|---|
| Ligand | BDBM50350311 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_762051 (CHEMBL1816043) |
|---|
| Kd | 5±n/a nM |
|---|
| Citation |  Ilies, M; Di Costanzo, L; Dowling, DP; Thorn, KJ; Christianson, DW Binding ofa,a-disubstituted amino acids to arginase suggests new avenues for inhibitor design. J Med Chem54:5432-43 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Arginase-1 |
|---|
| Name: | Arginase-1 |
|---|
| Synonyms: | ARG1 | ARGI1_HUMAN | Liver-type arginase | Type I arginase |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 34737.53 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_978893 |
|---|
| Residue: | 322 |
|---|
| Sequence: | MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
LACFGLAREGNHKPIDYLNPPK
|
|
|
|---|
| BDBM50350311 |
|---|
| n/a |
|---|
| Name | BDBM50350311 |
|---|
| Synonyms: | CHEMBL1812661 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C6H14BNO4 |
|---|
| Mol. Mass. | 174.991 |
|---|
| SMILES | [NH3+][C@@H](CCCCB(O)O)C([O-])=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
