| Reaction Details |
|---|
 | Report a problem with these data |
| Target | NUAK family SNF1-like kinase 1 |
|---|
| Ligand | BDBM50350424 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_762494 (CHEMBL1816864) |
|---|
| IC50 | 15600±n/a nM |
|---|
| Citation |  Ebada, SS; Schulz, B; Wray, V; Totzke, F; Kubbutat, MH; Müller, WE; Hamacher, A; Kassack, MU; Lin, W; Proksch, P Arthrinins A-D: novel diterpenoids and further constituents from the sponge derived fungus Arthrinium sp. Bioorg Med Chem19:4644-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| NUAK family SNF1-like kinase 1 |
|---|
| Name: | NUAK family SNF1-like kinase 1 |
|---|
| Synonyms: | ARK5 | KIAA0537 | NUAK1 | NUAK1_HUMAN | OMPHK1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 74326.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1451343 |
|---|
| Residue: | 661 |
|---|
| Sequence: | MEGAAAPVAGDRPDLGLGAPGSPREAVAGATAALEPRKPHGVKRHHHKHNLKHRYELQET
LGKGTYGKVKRATERFSGRVVAIKSIRKDKIKDEQDMVHIRREIEIMSSLNHPHIISIYE
VFENKDKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVHYCHKNGVVHRDLK
LENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPEIVNGRPYRGPEVDSWALG
VLLYTLVYGTMPFDGFDHKNLIRQISSGEYREPTQPSDARGLIRWMLMVNPDRRATIEDI
ANHWWVNWGYKSSVCDCDALHDSESPLLARIIDWHHRSTGLQADTEAKMKGLAKPTTSEV
MLERQRSLKKSKKENDFAQSGQDAVPESPSKLSSKRPKGILKKRSNSEHRSHSTGFIEGV
VGPALPSTFKMEQDLCRTGVLLPSSPEAEVPGKLSPKQSATMPKKGILKKTQQRESGYYS
SPERSESSELLDSNDVMGSSIPSPSPPDPARVTSHSLSCRRKGILKHSSKYSAGTMDPAL
VSPEMPTLESLSEPGVPAEGLSRSYSRPSSVISDDSVLSSDSFDLLDLQENRPARQRIRS
CVSAENFLQIQDFEGLQNRPRPQYLKRYRNRLADSSFSLLTDMDDVTQVYKQALEICSKL
N
|
|
|
|---|
| BDBM50350424 |
|---|
| n/a |
|---|
| Name | BDBM50350424 |
|---|
| Synonyms: | CHEMBL454440 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C14H10O6 |
|---|
| Mol. Mass. | 274.2256 |
|---|
| SMILES | Cc1c(O)c(O)cc2oc3cc(O)cc(O)c3c(=O)c12 |
|---|
| Structure | 
|
|---|
Search and Browse
