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TargetProstaglandin E2 receptor EP3 subtype
LigandBDBM50351484
Substrate/Competitorn/a
Meas. Tech.ChEMBL_764672 (CHEMBL1821224)
Ki>10000±n/a nM
Citation Iwahashi, MTakahashi, ETanaka, MMatsunaga, YOkada, YMatsumoto, RNambu, FNakai, HToda, M Design and synthesis of new prostaglandin D2 receptor antagonists. Bioorg Med Chem19:5361-71 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Prostaglandin E2 receptor EP3 subtype
Name:Prostaglandin E2 receptor EP3 subtype
Synonyms:PE2R3_MOUSE | PGE receptor, EP3 isoform alpha | Prostaglandin E2 receptor EP3 isoform alpha | Prostaglandin E3 | Prostanoid EP3 receptor | Ptger3 | Ptgerep3
Type:G-protein coupled receptor
Mol. Mass.:40092.50
Organism:Mus musculus (Mouse)
Description:n/a
Residue:365
Sequence:
MASMWAPEHSAEAHSNLSSTTDDCGSVSVAFPITMMVTGFVGNALAMLLVSRSYRRRESK
RKKSFLLCIGWLALTDLVGQLLTSPVVILVYLSQRRWEQLDPSGRLCTFFGLTMTVFGLS
SLLVASAMAVERALAIRAPHWYASHMKTRATPVLLGVWLSVLAFALLPVLGVGRYSVQWP
GTWCFISTGPAGNETDPAREPGSVAFASAFACLGLLALVVTFACNLATIKALVSRCRAKA
AVSQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLIMMLKMIFNQMSVEQCKTQMGKEKE
CNSFLIAVRLASLNQILDPWVYLLLRKILLRKFCQIRDHTNYASSSTSLPCPGSSALMWS
DQLER
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  Blast E-value cutoff:
BDBM50351484
n/a
NameBDBM50351484
Synonyms:CHEMBL1819623
TypeSmall organic molecule
Emp. Form.C25H22ClFN2O5
Mol. Mass.484.904
SMILESCN1C[C@@H](COc2ccc(C(=O)Nc3cc(CC(O)=O)ccc3F)c(Cl)c2)Oc2ccccc12 |r|
Structure
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