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TargetAutoinducer 1 sensor kinase/phosphatase luxN
LigandBDBM50351501
Substrate/Competitorn/a
Meas. Tech.ChEMBL_765226
IC50 2600±n/a nM
Citation Lowery CASalzameda NTSawada DKaufmann GFJanda KD Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem 53:7467-89 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Autoinducer 1 sensor kinase/phosphatase luxN
Name:Autoinducer 1 sensor kinase/phosphatase luxN
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:96099.26
Organism:Vibrio harveyi
Description:ChEMBL_765226
Residue:849
Sequence:
MFDFSLEAIVYAKAISLLATVAVVMMWLFYYCYRLKQKNEVIFGTHHAAYIAYSVCIIAW
ISSNAYFHTDLLPELGASAGMFMAKFANLASFFAFAFAYYFSCQLAAEQRKGKVHRWQQG
IFVSLTVYSLFINLRPGLTVEHVDIVGPSQFIIEFGPHTSYFFIGLVSFVVLTLVNLVAM
RTNSSKLTLAKTNYMIAGILVFMLSTAVIHLGMTYFMGDFSLTWLPPALSISEMLFVGYA
LLTSRFYSVKYIAYLALSVLLVCAIFVLPLGAIFIPLTESNQWLIAIPICALIGITWQLL
YKKTSRYASFLIYGDKKTPVQQILSLEEDFKLSIDDAMRRLGKLLQIPNDKLRLVTSNYN
ETFYEEYLSSNRSVLVFDELSEELEYKVSAKRSMKALYDKMSSNNTALVMPLFGQGKSVT
HLLISPHKSNNQMFSNEEISAVQTLLTRVQSTIEADRRIRQSRALANSIAHEMRNPLAQV
QLQFEALKQHIENHAPVEQITLDIENGQAAIQRGRQLIDIILREVSDSSPEHEPIAMTSI
HKAVDQAVSHYGFENEKIIERIRLPQHTDFVAKLNETLFNFVIFNLIRNAIYYFDSYPDS
QIEISTKTGPYENTLIFRDTGPGIDETISHKIFDDFFSYQKSGGSGLGLGYCQRVMRSFG
GRIECKSKLGTFTEFHLYFPVVPNAPKADTLRTPYFNDWKQNKRSNEHKVAPNVQINNQS
PTVLIVDDKEVQRALVQMYLNQLGVNSLQANNGENAVEVFKANHVDLILMDVQMPVMNGF
DASQRIKELSPQTPIVALSGESGERELDMINKLMDGRLEKPTTLNALRHVLGNWLNKNTA
SSACEAERE
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  Blast E-value cutoff:
BDBM50351501
n/a
NameBDBM50351501
Synonyms:CHEMBL1823948
TypeSmall organic molecule
Emp. Form.C19H12Cl2O3S
Mol. Mass.391.268
SMILESClc1ccc(cc1)C(=O)c1ccc(cc1)S(=O)(=O)c1ccc(Cl)cc1
Structure
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