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TargetAutoinducer 1 sensor kinase/phosphatase luxN
LigandBDBM50351502
Substrate/Competitorn/a
Meas. Tech.ChEMBL_765226
IC50 2900±n/a nM
Citation Lowery CASalzameda NTSawada DKaufmann GFJanda KD Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem 53:7467-89 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Autoinducer 1 sensor kinase/phosphatase luxN
Name:Autoinducer 1 sensor kinase/phosphatase luxN
Synonyms:n/a
Type:PROTEIN
Mol. Mass.:96099.26
Organism:Vibrio harveyi
Description:ChEMBL_765226
Residue:849
Sequence:
MFDFSLEAIVYAKAISLLATVAVVMMWLFYYCYRLKQKNEVIFGTHHAAYIAYSVCIIAW
ISSNAYFHTDLLPELGASAGMFMAKFANLASFFAFAFAYYFSCQLAAEQRKGKVHRWQQG
IFVSLTVYSLFINLRPGLTVEHVDIVGPSQFIIEFGPHTSYFFIGLVSFVVLTLVNLVAM
RTNSSKLTLAKTNYMIAGILVFMLSTAVIHLGMTYFMGDFSLTWLPPALSISEMLFVGYA
LLTSRFYSVKYIAYLALSVLLVCAIFVLPLGAIFIPLTESNQWLIAIPICALIGITWQLL
YKKTSRYASFLIYGDKKTPVQQILSLEEDFKLSIDDAMRRLGKLLQIPNDKLRLVTSNYN
ETFYEEYLSSNRSVLVFDELSEELEYKVSAKRSMKALYDKMSSNNTALVMPLFGQGKSVT
HLLISPHKSNNQMFSNEEISAVQTLLTRVQSTIEADRRIRQSRALANSIAHEMRNPLAQV
QLQFEALKQHIENHAPVEQITLDIENGQAAIQRGRQLIDIILREVSDSSPEHEPIAMTSI
HKAVDQAVSHYGFENEKIIERIRLPQHTDFVAKLNETLFNFVIFNLIRNAIYYFDSYPDS
QIEISTKTGPYENTLIFRDTGPGIDETISHKIFDDFFSYQKSGGSGLGLGYCQRVMRSFG
GRIECKSKLGTFTEFHLYFPVVPNAPKADTLRTPYFNDWKQNKRSNEHKVAPNVQINNQS
PTVLIVDDKEVQRALVQMYLNQLGVNSLQANNGENAVEVFKANHVDLILMDVQMPVMNGF
DASQRIKELSPQTPIVALSGESGERELDMINKLMDGRLEKPTTLNALRHVLGNWLNKNTA
SSACEAERE
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  Blast E-value cutoff:
BDBM50351502
n/a
NameBDBM50351502
Synonyms:CHEMBL1823947
TypeSmall organic molecule
Emp. Form.C21H25N3O4S2
Mol. Mass.447.571
SMILESCOc1ccc(CNC(=O)C(NS(=O)(=O)c2ccc3nc(C)sc3c2)C(C)C)cc1
Structure
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