| Reaction Details |
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 | Report a problem with these data |
| Target | Transcriptional activator protein LuxR |
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| Ligand | BDBM50241431 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_765231 (CHEMBL1827784) |
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| EC50 | 350±n/a nM |
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| Citation |  Lowery, CA; Salzameda, NT; Sawada, D; Kaufmann, GF; Janda, KD Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem53:7467-89 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Transcriptional activator protein LuxR |
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| Name: | Transcriptional activator protein LuxR |
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| Synonyms: | LUXR_ALIFS | luxR |
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| Type: | PROTEIN |
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| Mol. Mass.: | 28563.86 |
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| Organism: | Vibrio fischeri |
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| Description: | ChEMBL_831639 |
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| Residue: | 250 |
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| Sequence: | MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILD
NYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLIT
GFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSN
NDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILT
GAIDCPYFKN
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| BDBM50241431 |
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| n/a |
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| Name | BDBM50241431 |
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| Synonyms: | (S)-2-(3-nitrophenyl)-N-(2-oxo-tetrahydrofuran-3-yl)acetamide | (S)-2-(3-nitrophenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide | CHEMBL405298 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H12N2O5 |
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| Mol. Mass. | 264.2341 |
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| SMILES | [O-][N+](=O)c1cccc(CC(=O)N[C@H]2CCOC2=O)c1 |r| |
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| Structure | 
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