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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Histamine H3 receptor | ||
| Ligand | BDBM50352090 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_766550 (CHEMBL1827031) | ||
| Ki | 0.41±n/a nM | ||
| Citation |  Labeeuw, O; Levoin, N; Poupardin-Olivier, O; Calmels, T; Ligneau, X; Berrebi-Bertrand, I; Robert, P; Lecomte, JM; Schwartz, JC; Capet, M Novel and highly potent histamine H3 receptor ligands. Part 2: exploring the cyclohexylamine-based series. Bioorg Med Chem Lett21:5384-8 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Histamine H3 receptor | |||
| Name: | Histamine H3 receptor | ||
| Synonyms: | G-protein coupled receptor 97 | GPCR97 | HH3R | HISTAMINE H3 | HRH3 | HRH3_HUMAN | Histamine H3 receptor (H3) | Histamine H3L | Histamine receptor (H3 and H4) | ||
| Type: | G Protein-Coupled Receptor (GPCR) | ||
| Mol. Mass.: | 48691.47 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Binding assays were using CHO cells stably expressing hH3R receptors. | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50352090 | |||
| n/a | |||
| Name | BDBM50352090 | ||
| Synonyms: | CHEMBL1824241 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C24H38N2O2 | ||
| Mol. Mass. | 386.5707 | ||
| SMILES | C(COc1ccc(cc1)[C@H]1CC[C@@H](CC1)N1CCOCC1)CN1CCCCC1 |r,wU:12.16,wD:9.9,(21.81,-23.48,;23.35,-23.48,;24.12,-22.15,;25.66,-22.15,;26.43,-23.49,;27.96,-23.5,;28.74,-22.17,;27.97,-20.83,;26.43,-20.82,;30.28,-22.18,;31.04,-23.52,;32.58,-23.53,;33.36,-22.21,;32.6,-20.87,;31.05,-20.85,;34.9,-22.22,;35.65,-23.56,;37.19,-23.58,;37.97,-22.26,;37.22,-20.92,;35.67,-20.9,;21.04,-22.14,;19.5,-22.14,;18.74,-23.47,;17.2,-23.47,;16.42,-22.14,;17.2,-20.8,;18.74,-20.8,)| | ||
| Structure | 
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