| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Sphingosine 1-phosphate receptor 4 |
|---|
| Ligand | BDBM62407 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_766636 (CHEMBL1827202) |
|---|
| IC50 | 78±n/a nM |
|---|
| Citation |  Urbano, M; Guerrero, M; Zhao, J; Velaparthi, S; Schaeffer, MT; Brown, S; Rosen, H; Roberts, E SAR analysis of innovative selective small molecule antagonists of sphingosine-1-phosphate 4 (S1P4) receptor. Bioorg Med Chem Lett21:5470-4 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Sphingosine 1-phosphate receptor 4 |
|---|
| Name: | Sphingosine 1-phosphate receptor 4 |
|---|
| Synonyms: | EDG6 | Endothelial differentiation G-protein coupled receptor 6 | S1P receptor 4 | S1P receptor Edg-6 | S1P4 | S1PR4 | S1PR4_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor Edg-6 | Sphingosine-1-phosphate receptor 4 | sphingosine-1-phosphate 4 S1P4 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 41647.39 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 384 |
|---|
| Sequence: | MNATGTPVAPESCQQLAAGGHSRLIVLHYNHSGRLAGRGGPEDGGLGALRGLSVAASCLV
VLENLLVLAAITSHMRSRRWVYYCLVNITLSDLLTGAAYLANVLLSGARTFRLAPAQWFL
REGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGFIGLCWLLAALLGMLP
LLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGAIFRLVQASGQKAPRP
AARRKARRLLKTVLMILLAFLVCWGPLFGLLLADVFGSNLWAQEYLRGMDWILALAVLNS
AVNPIIYSFRSREVCRAVLSFLCCGCLRLGMRGPGDCLARAVEAHSGASTTDSSLRPRDS
FRGSRSLSFRMREPLSSISSVRSI
|
|
|
|---|
| BDBM62407 |
|---|
| n/a |
|---|
| Name | BDBM62407 |
|---|
| Synonyms: | 5-(2,5-dichlorophenyl)-N-(2,6-dimethylphenyl)-2-furamide | 5-(2,5-dichlorophenyl)-N-(2,6-dimethylphenyl)-2-furancarboxamide | 5-(2,5-dichlorophenyl)-N-(2,6-dimethylphenyl)furan-2-carboxamide | 5-[2,5-bis(chloranyl)phenyl]-N-(2,6-dimethylphenyl)furan-2-carboxamide | SR-02000000251 | SR-02000000251-1 | cid_4492589 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H15Cl2NO2 |
|---|
| Mol. Mass. | 360.234 |
|---|
| SMILES | Cc1cccc(C)c1NC(=O)c1ccc(o1)-c1cc(Cl)ccc1Cl |
|---|
| Structure | 
|
|---|
Search and Browse
