| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Carbonic anhydrase |
|---|
| Ligand | BDBM50352643 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_766490 (CHEMBL1826755) |
|---|
| pH | 8.3±n/a |
|---|
| Ki | 4990±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  Rami, M; Innocenti, A; Montero, JL; Scozzafava, A; Winum, JY; Supuran, CT Synthesis of rhodamine B-benzenesulfonamide conjugates and their inhibitory activity against humana- and bacterial/fungalß-carbonic anhydrases. Bioorg Med Chem Lett21:5210-3 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Carbonic anhydrase |
|---|
| Name: | Carbonic anhydrase |
|---|
| Synonyms: | CAN_CANAL | NCE103 | beta-Carbonic Anhydrase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 31587.59 |
|---|
| Organism: | Candida albicans (Yeast) |
|---|
| Description: | n/a |
|---|
| Residue: | 281 |
|---|
| Sequence: | MGRENILKYQLEHDHESDLVTEKDQSLLLDNNNNLNGMNNTIKTHPVRVSSGNHNNFPFT
LSSESTLQDFLNNNKFFVDSIKHNHGNQIFDLNGQGQSPHTLWIGCSDSRAGDQCLATLP
GEIFVHRNIANIVNANDISSQGVIQFAIDVLKVKKIIVCGHTDCGGIWASLSKKKIGGVL
DLWLNPVRHIRAANLKLLEEYNQDPKLKAKKLAELNVISSVTALKRHPSASVALKKNEIE
VWGMLYDVATGYLSQVEIPQDEFEDLFHVHDEHDEEEYNPH
|
|
|
|---|
| BDBM50352643 |
|---|
| n/a |
|---|
| Name | BDBM50352643 |
|---|
| Synonyms: | CHEMBL1822699 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C34H36N4O4S |
|---|
| Mol. Mass. | 596.739 |
|---|
| SMILES | CCN(CC)c1ccc2c(Oc3cc(ccc3C22N(C(=O)c3ccccc23)c2ccc(cc2)S(N)(=O)=O)N(CC)CC)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
