| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cytosol aminopeptidase |
|---|
| Ligand | BDBM50353015 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_766294 (CHEMBL1826226) |
|---|
| Ki | >100000±n/a nM |
|---|
| Citation |  Maiereanu, C; Schmitt, C; Schifano-Faux, N; Le Nouën, D; Defoin, A; Tarnus, C A novel amino-benzosuberone derivative is a picomolar inhibitor of mammalian aminopeptidase N/CD13. Bioorg Med Chem19:5716-33 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cytosol aminopeptidase |
|---|
| Name: | Cytosol aminopeptidase |
|---|
| Synonyms: | AMPL_BOVIN | LAP | LAP3 | LAPc | Leucine Aminopeptidase | Leucyl aminopeptidase |
|---|
| Type: | Homohexamer |
|---|
| Mol. Mass.: | 56288.28 |
|---|
| Organism: | Bos taurus (bovine) |
|---|
| Description: | Bovine kidney LAPc was purchased from Sigma Chemical Co. |
|---|
| Residue: | 519 |
|---|
| Sequence: | MFLLPLPAAARVAVRHLSVKRLWAPGPAAADMTKGLVLGIYSKEKEEDEPQFTSAGENFN
KLVSGKLREILNISGPPLKAGKTRTFYGLHEDFPSVVVVGLGKKTAGIDEQENWHEGKEN
IRAAVAAGCRQIQDLEIPSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKRKVVVSAKLHGS
EDQEAWQRGVLFASGQNLARRLMETPANEMTPTKFAEIVEENLKSASIKTDVFIRPKSWI
EEQEMGSFLSVAKGSEEPPVFLEIHYKGSPNASEPPLVFVGKGITFDSGGISIKAAANMD
LMRADMGGAATICSAIVSAAKLDLPINIVGLAPLCENMPSGKANKPGDVVRARNGKTIQV
DNTDAEGRLILADALCYAHTFNPKVIINAATLTGAMDIALGSGATGVFTNSSWLWNKLFE
ASIETGDRVWRMPLFEHYTRQVIDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHL
DIAGVMTNKDEVPYLRKGMAGRPTRTLIEFLFRFSQDSA
|
|
|
|---|
| BDBM50353015 |
|---|
| n/a |
|---|
| Name | BDBM50353015 |
|---|
| Synonyms: | CHEMBL1821977 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H12BrNO |
|---|
| Mol. Mass. | 254.123 |
|---|
| SMILES | NC1CCc2cccc(Br)c2CC1=O |
|---|
| Structure | 
|
|---|
Search and Browse
