| Reaction Details |
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 | Report a problem with these data |
| Target | Integrin-linked protein kinase |
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| Ligand | BDBM50353484 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_768900 (CHEMBL1832067) |
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| IC50 | 600±n/a nM |
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| Citation |  Lee, SL; Hsu, EC; Chou, CC; Chuang, HC; Bai, LY; Kulp, SK; Chen, CS Identification and characterization of a novel integrin-linked kinase inhibitor. J Med Chem54:6364-74 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrin-linked protein kinase |
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| Name: | Integrin-linked protein kinase |
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| Synonyms: | ILK | ILK1 | ILK2 | ILK_HUMAN | Integrin-linked protein kinase (ILK) | Serine/threonine-protein kinase ILK-1 |
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| Type: | Protein |
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| Mol. Mass.: | 51429.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13418 |
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| Residue: | 452 |
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| Sequence: | MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI
NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV
ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG
TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP
RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD
MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA
LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH
VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK
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| BDBM50353484 |
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| n/a |
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| Name | BDBM50353484 |
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| Synonyms: | CHEMBL1830587 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H30F3N5O |
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| Mol. Mass. | 533.5873 |
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| SMILES | CNC(=O)CCc1cc(-c2ccc(cc2)-c2ccc(cc2)C(F)(F)F)n(n1)-c1ccc(cc1)N1CCNCC1 |
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| Structure | 
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