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TargetThromboxane A2 receptor
LigandBDBM50353635
Substrate/Competitorn/a
Meas. Tech.ChEMBL_769881 (CHEMBL1831974)
Kd 19±n/a nM
Citation Ballatore, CSoper, JHPiscitelli, FJames, MHuang, LAtasoylu, OHuryn, DMTrojanowski, JQLee, VMBrunden, KRSmith, AB Cyclopentane-1,3-dione: a novel isostere for the carboxylic acid functional group. Application to the design of potent thromboxane (A2) receptor antagonists. J Med Chem54:6969-83 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Thromboxane A2 receptor
Name:Thromboxane A2 receptor
Synonyms:TA2R_MOUSE | Tbxa2r | Thromboxane A2
Type:Enzyme Catalytic Domain
Mol. Mass.:37114.77
Organism:MOUSE
Description:Thromboxane A2 TBXA2R MOUSE::P30987
Residue:341
Sequence:
MWPNGTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRS
SFLALLCGLVLTDFLGLLVTGAIVASQHAALLDWRATDPSCRLCYFMGVAMVFFGLCPLL
LGAAMASERFVGITRPFSRPTATSRRAWATVGLVWVAAGALGLLPLLGLGRYSVQYPGSW
CFLTLGTQRGDVVFGLIFALLGSASVGLSLLLNTVSVATLCRVYHTREATQRPRDCEVEM
MVQLVGIMVVATVCWMPLLVFIMQTLLQTPPVMSFSGQLLRATEHQLLIYLRVATWNQIL
DPWVYILFRRSVLRRLHPRFSSQLQAVSLRRPPAQAMLSGP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50353635
n/a
NameBDBM50353635
Synonyms:CHEMBL1829801
TypeSmall organic molecule
Emp. Form.C17H18ClN5O2S
Mol. Mass.391.875
SMILESClc1ccc(cc1)S(=O)(=O)NCCc1cccc(CCc2nnn[nH]2)c1
Structure
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