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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Neuropeptide Y receptor type 5 | ||
| Ligand | BDBM50354074 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_770872 (CHEMBL1837820) | ||
| Ki | 21.5±n/a nM | ||
| Citation |  Packiarajan, M; Marzabadi, MR; Desai, M; Lu, Y; Noble, SA; Wong, WC; Jubian, V; Chandrasena, G; Wolinsky, TD; Zhong, H; Walker, MW; Wiborg, O; Andersen, K Discovery of Lu AA33810: a highly selective and potent NPY5 antagonist with in vivo efficacy in a model of mood disorder. Bioorg Med Chem Lett21:5436-41 (2011) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Neuropeptide Y receptor type 5 | |||
| Name: | Neuropeptide Y receptor type 5 | ||
| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 50746.64 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q15761 | ||
| Residue: | 445 | ||
| Sequence: |
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| BDBM50354074 | |||
| n/a | |||
| Name | BDBM50354074 | ||
| Synonyms: | CHEMBL1836315 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H27N5O2S3 | ||
| Mol. Mass. | 489.677 | ||
| SMILES | Cn1cnc(c1)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)Nc1nc-2c(CCSc3ccccc-23)s1 |r,wU:11.11,wD:14.18,(18.91,-20.53,;19.83,-19.3,;21.38,-19.32,;21.87,-17.85,;20.63,-16.93,;19.38,-17.82,;20.65,-15.38,;22.19,-15.4,;21.44,-14.06,;19.32,-14.59,;19.34,-13.05,;18.02,-12.26,;16.67,-13.02,;15.34,-12.23,;15.37,-10.69,;16.7,-9.92,;18.03,-10.72,;14.04,-9.9,;12.69,-10.66,;11.33,-10.04,;10.32,-11.15,;11.05,-12.45,;10.43,-13.93,;8.93,-14.32,;7.72,-13.38,;7.68,-11.78,;6.29,-11.26,;6.04,-9.8,;7.19,-8.85,;8.59,-9.37,;8.83,-10.84,;12.52,-12.15,)| | ||
| Structure | 
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