| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 2 |
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| Ligand | BDBM50354135 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_770827 (CHEMBL1837632) |
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| IC50 | 40.10±n/a nM |
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| Citation |  Cichero, E; Ligresti, A; Allarà, M; di Marzo, V; Lazzati, Z; D'Ursi, P; Marabotti, A; Milanesi, L; Spallarossa, A; Ranise, A; Fossa, P Homology modeling in tandem with 3D-QSAR analyses: a computational approach to depict the agonist binding site of the human CB2 receptor. Eur J Med Chem46:4489-505 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 2 |
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| Name: | Cannabinoid receptor 2 |
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| Synonyms: | CANNABINOID CB2 | CB-2 | CB2 | CB2A | CB2B | CNR2 | CNR2_HUMAN | CX5 | Cannabinoid CB2 receptor | Cannabinoid receptor 2 (CB2) | Cannabinoid receptor 2 (CB2R) | hCB2 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 39690.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P34972 |
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| Residue: | 360 |
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| Sequence: | MEECWVTEIANGSKDGLDSNPMKDYMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILS
SHQLRRKPSYLFIGSLAGADFLASVVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTAS
VGSLLLTAIDRYLCLRYPPSYKALLTRGRALVTLGIMWVLSALVSYLPLMGWTCCPRPCS
ELFPLIPNDYLLSWLLFIAFLFSGIIYTYGHVLWKAHQHVASLSGHQDRQVPGMARMRLD
VRLAKTLGLVLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYA
LRSGEIRSSAHHCLAHWKKCVRGLGSEAKEEAPRSSVTETEADGKITPWPDSRDLDLSDC
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| BDBM50354135 |
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| n/a |
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| Name | BDBM50354135 |
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| Synonyms: | CHEMBL1836189 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H23N3O3S |
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| Mol. Mass. | 421.512 |
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| SMILES | O=S(=O)(C(=C\c1cn(CCN2CCOCC2)c2ccccc12)\C#N)c1ccccc1 |
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| Structure | 
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