| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 2C |
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| Ligand | BDBM50354585 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_771222 (CHEMBL1839304) |
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| Ki | >1000±n/a nM |
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| Citation |  van Loevezijn, A; Venhorst, J; Iwema Bakker, WI; de Korte, CG; de Looff, W; Verhoog, S; van Wees, JW; van Hoeve, M; van de Woestijne, RP; van der Neut, MA; Borst, AJ; van Dongen, MJ; de Bruin, NM; Keizer, HG; Kruse, CG N'-(arylsulfonyl)pyrazoline-1-carboxamidines as novel, neutral 5-hydroxytryptamine 6 receptor (5-HT6R) antagonists with unique structural features. J Med Chem54:7030-54 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 2C |
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| Name: | 5-hydroxytryptamine receptor 2C |
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| Synonyms: | 5-HT-2C | 5-HT2C | 5-HT2C-INI | 5-HT2c VGI | 5-HTR2C | 5-hydroxytryptamine receptor 1C | 5-hydroxytryptamine receptor 2C (5-HT-2C) | 5-hydroxytryptamine receptor 2C (5HT-2C) | 5HT-1C | 5HT2C_HUMAN | HTR1C | HTR2C | Serotonin (5-HT3) receptor | Serotonin 2c (5-HT2c) receptor | Serotonin Receptor 2C |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 51836.79 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P28335 |
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| Residue: | 458 |
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| Sequence: | MVNLRNAVHSFLVHLIGLLVWQCDISVSPVAAIVTDIFNTSDGGRFKFPDGVQNWPALSI
VIIIIMTIGGNILVIMAVSMEKKLHNATNYFLMSLAIADMLVGLLVMPLSLLAILYDYVW
PLPRYLCPVWISLDVLFSTASIMHLCAISLDRYVAIRNPIEHSRFNSRTKAIMKIAIVWA
ISIGVSVPIPVIGLRDEEKVFVNNTTCVLNDPNFVLIGSFVAFFIPLTIMVITYCLTIYV
LRRQALMLLHGHTEEPPGLSLDFLKCCKRNTAEEENSANPNQDQNARRRKKKERRPRGTM
QAINNERKASKVLGIVFFVFLIMWCPFFITNILSVLCEKSCNQKLMEKLLNVFVWIGYVC
SGINPLVYTLFNKIYRRAFSNYLRCNYKVEKKPPVRQIPRVAATALSGRELNVNIYRHTN
EPVIEKASDNEPGIEMQVENLELPVNPSSVVSERISSV
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| BDBM50354585 |
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| n/a |
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| Name | BDBM50354585 |
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| Synonyms: | CHEMBL1834226 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H19ClN4O2S |
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| Mol. Mass. | 342.844 |
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| SMILES | CCN=C(NS(=O)(=O)c1cccc(Cl)c1)N1CC(CC)C=N1 |w:2.1,c:21| |
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| Structure | 
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