| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50354844 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_772345 (CHEMBL1838790) |
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| Ki | 1900±n/a nM |
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| Citation |  Teng, H; Thakur, GA; Makriyannis, A Conformationally constrained analogs of BAY 59-3074 as novel cannabinoid receptor ligands. Bioorg Med Chem Lett21:5999-6002 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_RAT | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cnr1 | Skr6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 52856.55 |
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| Organism: | Rattus norvegicus (rat) |
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| Description: | P20272 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEENIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50354844 |
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| n/a |
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| Name | BDBM50354844 |
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| Synonyms: | CHEMBL1834522 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H11F6NO4S |
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| Mol. Mass. | 451.34 |
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| SMILES | FC(F)(F)CCCS(=O)(=O)Oc1cccc2oc3c(C#N)c(ccc3c12)C(F)(F)F |
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| Structure | 
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