Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Kallikrein-7 | ||
Ligand | BDBM50355086 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_772793 (CHEMBL1837532) | ||
Ki | 12200±n/a nM | ||
Citation | Teixeira, TS; Freitas, RF; Abrahão, O; Devienne, KF; de Souza, LR; Blaber, SI; Blaber, M; Kondo, MY; Juliano, MA; Juliano, L; Puzer, L Biological evaluation and docking studies of natural isocoumarins as inhibitors for human kallikrein 5 and 7. Bioorg Med Chem Lett21:6112-5 (2011) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Kallikrein-7 | |||
Name: | Kallikrein-7 | ||
Synonyms: | KLK7 | KLK7_HUMAN | Kallikrein 7 | Kallikrein-7 | PRSS6 | SCCE | Serine protease 6 | Stratum corneum chymotryptic enzyme | hK7 | hSCCE | kallikrein-7 isoform 1 preproprotein | ||
Type: | PROTEIN | ||
Mol. Mass.: | 27535.05 | ||
Organism: | Homo sapiens (Human) | ||
Description: | ChEMBL_1469257 | ||
Residue: | 253 | ||
Sequence: |
| ||
BDBM50355086 | |||
n/a | |||
Name | BDBM50355086 | ||
Synonyms: | CHEMBL1834753 | ||
Type | Small organic molecule | ||
Emp. Form. | C32H26O12 | ||
Mol. Mass. | 602.5416 | ||
SMILES | COc1cc2c(OC)c3cc(C)oc(=O)c3c(O)c2c(O)c1-c1c(OC)cc2c(OC)c3cc(C)oc(=O)c3c(O)c2c1O |(17.28,-41.71,;17.28,-40.17,;15.95,-39.4,;14.61,-40.16,;13.28,-39.39,;11.96,-40.17,;11.96,-41.71,;10.63,-42.48,;10.62,-39.4,;9.29,-40.18,;7.95,-39.4,;6.61,-40.17,;7.95,-37.85,;9.29,-37.09,;9.3,-35.55,;10.62,-37.86,;11.95,-37.08,;11.95,-35.54,;13.29,-37.85,;14.62,-37.09,;14.61,-35.55,;15.95,-37.85,;17.28,-37.08,;17.28,-35.53,;15.94,-34.76,;15.94,-33.22,;18.61,-34.76,;19.94,-35.53,;21.27,-34.76,;21.26,-33.22,;22.59,-32.44,;22.6,-35.52,;23.94,-34.75,;25.28,-35.53,;26.61,-34.76,;25.27,-37.07,;23.93,-37.84,;23.93,-39.38,;22.6,-37.07,;21.27,-37.84,;21.27,-39.38,;19.94,-37.07,;18.61,-37.84,;18.61,-39.38,)| | ||
Structure |