| Reaction Details |
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 | Report a problem with these data |
| Target | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase |
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| Ligand | BDBM50355115 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_772123 (CHEMBL1838042) |
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| IC50 | 13000±n/a nM |
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| Citation |  Tang, M; Odejinmi, SI; Allette, YM; Vankayalapati, H; Lai, K Identification of novel small molecule inhibitors of 4-diphosphocytidyl-2-C-methyl-D-erythritol (CDP-ME) kinase of Gram-negative bacteria. Bioorg Med Chem19:5886-95 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase |
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| Name: | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase |
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| Synonyms: | 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase | CMK | ISPE_YERPE | ipk | ispE |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32675.02 |
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| Organism: | Yersinia pestis |
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| Description: | ChEMBL_772123 |
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| Residue: | 299 |
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| Sequence: | MTTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQ
IRLLTPIAGVENEQNLIVRAAKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAAT
VLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFAEGIGEKLQPAEPVEKWYLVI
HPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYA
PSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR
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| BDBM50355115 |
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| n/a |
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| Name | BDBM50355115 |
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| Synonyms: | CHEMBL1835595 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10ClNO3 |
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| Mol. Mass. | 287.698 |
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| SMILES | Clc1ccc(cc1)-c1ccc(C=c2c(=C)[nH]oc2=O)o1 |w:11.11| |
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| Structure | 
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