Reaction Details |
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Target | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase |
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Ligand | BDBM50355117 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_772123 (CHEMBL1838042) |
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IC50 | 6000±n/a nM |
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Citation | Tang, M; Odejinmi, SI; Allette, YM; Vankayalapati, H; Lai, K Identification of novel small molecule inhibitors of 4-diphosphocytidyl-2-C-methyl-D-erythritol (CDP-ME) kinase of Gram-negative bacteria. Bioorg Med Chem19:5886-95 (2011) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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4-diphosphocytidyl-2-C-methyl-D-erythritol kinase |
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Name: | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase |
Synonyms: | 4-(cytidine-5'-diphospho)-2-C-methyl-D-erythritol kinase | CMK | ISPE_YERPE | ipk | ispE |
Type: | PROTEIN |
Mol. Mass.: | 32675.02 |
Organism: | Yersinia pestis |
Description: | ChEMBL_772123 |
Residue: | 299 |
Sequence: | MTTANQPICPSPAKWPSPAKLNLFLYITGQRADGYHQLQTLFQFLDYGDQLTIEPRDDNQ
IRLLTPIAGVENEQNLIVRAAKMLQKHPGNTPVPRGADISIDKCLPMGGGLGGGSSNAAT
VLVALNLLWQCGLTDEQLADLGLTLGADVPVFVRGHAAFAEGIGEKLQPAEPVEKWYLVI
HPGVNIPTPIIFSDPELKRNTPIRPLAALLSTPYANDCEPIARKRFREVEQALSWLLEYA
PSRLTGTGACVFAEFDTESSARQVLSIAPEWLHGFVARGVNVSPLHRVRSGKIESSERR
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BDBM50355117 |
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n/a |
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Name | BDBM50355117 |
Synonyms: | CHEMBL1835608 |
Type | Small organic molecule |
Emp. Form. | C15H11NO3 |
Mol. Mass. | 253.2527 |
SMILES | C=c1[nH]oc(=O)c1=Cc1ccc(o1)-c1ccccc1 |w:7.8| |
Structure |
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