| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cyclin-dependent kinase-like 2 |
|---|
| Ligand | BDBM50308060 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_774408 (CHEMBL1908625) |
|---|
| Kd | 43±n/a nM |
|---|
| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cyclin-dependent kinase-like 2 |
|---|
| Name: | Cyclin-dependent kinase-like 2 |
|---|
| Synonyms: | 2.7.11.22 | CDKL2 | CDKL2_HUMAN | Protein kinase p56 KKIAMRE | Serine/threonine-protein kinase KKIAMRE |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 56031.51 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q92772 |
|---|
| Residue: | 493 |
|---|
| Sequence: | MEKYENLGLVGEGSYGMVMKCRNKDTGRIVAIKKFLESDDDKMVKKIAMREIKLLKQLRH
ENLVNLLEVCKKKKRWYLVFEFVDHTILDDLELFPNGLDYQVVQKYLFQIINGIGFCHSH
NIIHRDIKPENILVSQSGVVKLCDFGFARTLAAPGEVYTDYVATRWYRAPELLVGDVKYG
KAVDVWAIGCLVTEMFMGEPLFPGDSDIDQLYHIMMCLGNLIPRHQELFNKNPVFAGVRL
PEIKEREPLERRYPKLSEVVIDLAKKCLHIDPDKRPFCAELLHHDFFQMDGFAERFSQEL
QLKVQKDARNVSLSKKSQNRKKEKEKDDSLVEERKTLVVQDTNADPKIKDYKLFKIKGSK
IDGEKAEKGNRASNASCLHDSRTSHNKIVPSTSLKDCSNVSVDHTRNPSVAIPPLTHNLS
AVAPSINSGMGTETIPIQGYRVDEKTKKCSIPFVKPNRHSPSGIYNINVTTLVSGPPLSD
DSGADLPQMEHQH
|
|
|
|---|
| BDBM50308060 |
|---|
| n/a |
|---|
| Name | BDBM50308060 |
|---|
| Synonyms: | 16-hydroxy-16-(hydroxymethyl)-15-methyl-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1^{15,18}.0^{2,6}.0^{7,27}.0^{8,13}.0^{19,26}.0^{20,25}]octacosa-1(26),2(6),7(27),8(13),9,11,20(25),21,23-nonaen-3-one | CEP-701 | CHEMBL603469 | US11370779, Compound CEP-701 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C26H21N3O4 |
|---|
| Mol. Mass. | 439.4626 |
|---|
| SMILES | C[C@]12O[C@H](C[C@]1(O)CO)n1c3ccccc3c3c4C(=O)NCc4c4c5ccccc5n2c4c13 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
