| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Myotonin-protein kinase |
|---|
| Ligand | BDBM50309910 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_774430 (CHEMBL1908647) |
|---|
| Kd | >10000±n/a nM |
|---|
| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Myotonin-protein kinase |
|---|
| Name: | Myotonin-protein kinase |
|---|
| Synonyms: | DM1PK | DMPK | DMPK_HUMAN | MDPK |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 69359.66 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_47059024 |
|---|
| Residue: | 629 |
|---|
| Sequence: | MSAEVRLRRLQQLVLDPGFLGLEPLLDLLLGVHQELGASELAQDKYVADFLQWAEPIVVR
LKEVRLQRDDFEILKVIGRGAFSEVAVVKMKQTGQVYAMKIMNKWDMLKRGEVSCFREER
DVLVNGDRRWITQLHFAFQDENYLYLVMEYYVGGDLLTLLSKFGERIPAEMARFYLAEIV
MAIDSVHRLGYVHRDIKPDNILLDRCGHIRLADFGSCLKLRADGTVRSLVAVGTPDYLSP
EILQAVGGGPGTGSYGPECDWWALGVFAYEMFYGQTPFYADSTAETYGKIVHYKEHLSLP
LVDEGVPEEARDFIQRLLCPPETRLGRGGAGDFRTHPFFFGLDWDGLRDSVPPFTPDFEG
ATDTCNFDLVEDGLTAMVSGGGETLSDIREGAPLGVHLPFVGYSYSCMALRDSEVPGPTP
MELEAEQLLEPHVQAPSLEPSVSPQDETAEVAVPAAVPAAEAEAEVTLRELQEALEEEVL
TRQSLSREMEAIRTDNQNFASQLREAEARNRDLEAHVRQLQERMELLQAEGATAVTGVPS
PRATDPPSHLDGPPAVAVGQCPLVGPGPMHRRHLLLPARVPRPGLSEALSLLLFAVVLSR
AAALGCIGLVAHAGQLTAVWRRPGAARAP
|
|
|
|---|
| BDBM50309910 |
|---|
| n/a |
|---|
| Name | BDBM50309910 |
|---|
| Synonyms: | CHEMBL608154 | ML-120B | N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H15ClN4O2 |
|---|
| Mol. Mass. | 366.801 |
|---|
| SMILES | COc1c(Cl)cc2c3ccncc3[nH]c2c1NC(=O)c1cccnc1C |
|---|
| Structure | 
|
|---|
Search and Browse
