| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase SRPK3 |
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| Ligand | BDBM50237710 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_774558 |
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| Kd | >10000±n/a nM |
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| Citation |  Davis MI; Hunt JP; Herrgard S; Ciceri P; Wodicka LM; Pallares G; Hocker M; Treiber DK; Zarrinkar PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol 29:1046-51 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase SRPK3 |
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| Name: | Serine/threonine-protein kinase SRPK3 |
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| Synonyms: | MSSK-1 | Muscle-specific serine kinase 1 | SR-protein-specific kinase 3 | SRSF protein kinase 3 | Serine/arginine-rich protein-specific kinase 3 | Serine/threonine-protein kinase 23 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 62021.04 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_655942 |
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| Residue: | 567 |
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| Sequence: | MSASTGGGGDSGGSGGSSSSSQASCGPESSGSELALATPVPQMLQGLLGSDDEEQEDPKD
YCKGGYHPVKIGDVFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETA
VDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNY
QGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQA
GAPPPSRSIVSTAPQEVLQTGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAATQ
AEDSGLRLDGGSGSTSSSGCHPGGARAGPSPASSSPAPGGGRSLSAGSQTSGFSGSLFSP
ASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHF
TEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAH
IVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSA
FLLPMMEYIPEKRASAADCLQHPWLNP
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| BDBM50237710 |
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| n/a |
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| Name | BDBM50237710 |
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| Synonyms: | 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide | AMN 107 | AMN107 | CHEMBL255863 | NILOTINIB |
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| Type | Small organic molecule |
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| Emp. Form. | C28H22F3N7O |
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| Mol. Mass. | 529.5158 |
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| SMILES | Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc(c1)C(F)(F)F |
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| Structure | 
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