| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase N2 |
|---|
| Ligand | BDBM50355496 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_774530 (CHEMBL1908747) |
|---|
| Kd | 880±n/a nM |
|---|
| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein kinase N2 |
|---|
| Name: | Serine/threonine-protein kinase N2 |
|---|
| Synonyms: | PKN2 | PKN2_HUMAN | PRK2 | PRKCL2 | Protein kinase C-like 2 | Protein kinase N2 | Protein-kinase C-related kinase 2 | Serine/threonine-protein kinase N2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 112029.78 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1433151 |
|---|
| Residue: | 984 |
|---|
| Sequence: | MASNPERGEILLTELQGDSRSLPFSENVSAVQKLDFSDTMVQQKLDDIKDRIKREIRKEL
KIKEGAENLRKVTTDKKSLAYVDNILKKSNKKLEELHHKLQELNAHIVVSDPEDITDCPR
TPDTPNNDPRCSTSNNRLKALQKQLDIELKVKQGAENMIQMYSNGSSKDRKLHGTAQQLL
QDSKTKIEVIRMQILQAVQTNELAFDNAKPVISPLELRMEELRHHFRIEFAVAEGAKNVM
KLLGSGKVTDRKALSEAQARFNESSQKLDLLKYSLEQRLNEVPKNHPKSRIIIEELSLVA
ASPTLSPRQSMISTQNQYSTLSKPAALTGTLEVRLMGCQDILENVPGRSKATSVALPGWS
PSETRSSFMSRTSKSKSGSSRNLLKTDDLSNDVCAVLKLDNTVVGQTSWKPISNQSWDQK
FTLELDRSRELEISVYWRDWRSLCAVKFLRLEDFLDNQRHGMCLYLEPQGTLFAEVTFFN
PVIERRPKLQRQKKIFSKQQGKTFLRAPQMNINIATWGRLVRRAIPTVNHSGTFSPQAPV
PTTVPVVDVRIPQLAPPASDSTVTKLDFDLEPEPPPAPPRASSLGEIDESSELRVLDIPG
QDSETVFDIQNDRNSILPKSQSEYKPDTPQSGLEYSGIQELEDRRSQQRFQFNLQDFRCC
AVLGRGHFGKVLLAEYKNTNEMFAIKALKKGDIVARDEVDSLMCEKRIFETVNSVRHPFL
VNLFACFQTKEHVCFVMEYAAGGDLMMHIHTDVFSEPRAVFYAACVVLGLQYLHEHKIVY
RDLKLDNLLLDTEGFVKIADFGLCKEGMGYGDRTSTFCGTPEFLAPEVLTETSYTRAVDW
WGLGVLIYEMLVGESPFPGDDEEEVFDSIVNDEVRYPRFLSTEAISIMRRLLRRNPERRL
GASEKDAEDVKKHPFFRLIDWSALMDKKVKPPFIPTIRGREDVSNFDDEFTSEAPILTPP
REPRILSEEEQEMFRDFDYIADWC
|
|
|
|---|
| BDBM50355496 |
|---|
| n/a |
|---|
| Name | BDBM50355496 |
|---|
| Synonyms: | CHEMBL1908397 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H20N4O |
|---|
| Mol. Mass. | 332.399 |
|---|
| SMILES | O=C(N1CCNCC1)c1ccc(\C=C\c2n[nH]c3ccccc23)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
