| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cyclin-dependent kinase 15 |
|---|
| Ligand | BDBM50331096 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_774198 (CHEMBL1908415) |
|---|
| Kd | >10000±n/a nM |
|---|
| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Cyclin-dependent kinase 15 |
|---|
| Name: | Cyclin-dependent kinase 15 |
|---|
| Synonyms: | ALS2CR7 | Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein | CDK15 | CDK15_HUMAN | Cell division protein kinase 15 | PFTK2 | Serine/threonine-protein kinase ALS2CR7 | Serine/threonine-protein kinase PFTAIRE-2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49029.02 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_655517 |
|---|
| Residue: | 435 |
|---|
| Sequence: | MGQELCAKTVQPGCSCYHCSEGGEAHSCRRSQPETTEAAFKLTDLKEASCSMTSFHPRGL
QAARAQKFKSKRPRSNSDCFQEEDLRQGFQWRKSLPFGAASSYLNLEKLGEGSYATVYKG
ISRINGQLVALKVISMNAEEGVPFTAIREASLLKGLKHANIVLLHDIIHTKETLTFVFEY
MHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVLHRDLKPQNLLISHLGELKL
ADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSELDIWGAGCIFIEMFQGQPLF
PGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEA
EDLASQMLKGFPRDRVSAQEALVHDYFSALPSQLYQLPDEESLFTVSGVRLKPEMCDLLA
SYQKGHHPAQFSKCW
|
|
|
|---|
| BDBM50331096 |
|---|
| n/a |
|---|
| Name | BDBM50331096 |
|---|
| Synonyms: | 4-(4-fluoro-2-methyl-1H-indol-5-yloxy)-6-methoxy-7-(3-(pyrrolidin-1-yl)propoxy)quinazoline | CHEMBL491473 | Cediranib | US10464902, Cediranib | ZD-2171 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C25H27FN4O3 |
|---|
| Mol. Mass. | 450.5053 |
|---|
| SMILES | COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCCC1 |
|---|
| Structure | 
|
|---|
Search and Browse
