| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Casein kinase I isoform alpha-like |
|---|
| Ligand | BDBM17055 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_774203 (CHEMBL1908420) |
|---|
| Kd | >10000±n/a nM |
|---|
| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Casein kinase I isoform alpha-like |
|---|
| Name: | Casein kinase I isoform alpha-like |
|---|
| Synonyms: | CSNK1A1L | Casein kinase I isoform alpha-like | KC1AL_HUMAN |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 39105.63 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_586447 |
|---|
| Residue: | 337 |
|---|
| Sequence: | MTNNSGSKAELVVGGKYKLVRKIGSGSFGDVYLGITTTNGEDVAVKLESQKVKHPQLLYE
SKLYTILQGGVGIPHMHWYGQEKDNNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
ISRIEYVHTKNFLHRDIKPDNFLMGTGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKH
LIGTVRYASINAHLGIEQSRRDDMESLGYVFMYFNRTSLPWQGLRAMTKKQKYEKISEKK
MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEVPDYMYLRQLFRILFRTLNHQYDYTFDWTM
LKQKAAQQAASSSGQGQQAQTQTGKQTEKNKNNVKDN
|
|
|
|---|
| BDBM17055 |
|---|
| n/a |
|---|
| Name | BDBM17055 |
|---|
| Synonyms: | (18S)-18-[(dimethylamino)methyl]-17-oxa-4,14,21-triazahexacyclo[19.6.1.1^{7,14}.0^{2,6}.0^{8,13}.0^{22,27}]nonacosa-1(28),2(6),7(29),8(13),9,11,22(27),23,25-nonaene-3,5-dione | (9S)-9-[(dimethylamino)methyl]-6,7,10,11-tetrahydro-9H,18H-5,21:12,17-di(metheno)dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecine-18,20(19H)-dione | K00587a | LY 333531 | LY-333531 | LY333531 | Ruboxistaurin | cid_153999 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C28H28N4O3 |
|---|
| Mol. Mass. | 468.5469 |
|---|
| SMILES | CN(C)C[C@@H]1CCn2cc(C3=C(C(=O)NC3=O)c3cn(CCO1)c1ccccc31)c1ccccc21 |r,t:10| |
|---|
| Structure | 
|
|---|
Search and Browse
