| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Serine/threonine-protein kinase OSR1 |
|---|
| Ligand | BDBM50309910 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_774457 (CHEMBL1908674) |
|---|
| Kd | >10000±n/a nM |
|---|
| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Serine/threonine-protein kinase OSR1 |
|---|
| Name: | Serine/threonine-protein kinase OSR1 |
|---|
| Synonyms: | KIAA1101 | OSR1 | OXSR1 | OXSR1_HUMAN | Oxidative stress-responsive 1 protein |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 58020.49 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_655500 |
|---|
| Residue: | 527 |
|---|
| Sequence: | MSEDSSALPWSINRDDYELQEVIGSGATAVVQAAYCAPKKEKVAIKRINLEKCQTSMDEL
LKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDE
STIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRN
KVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPPMKVLMLTL
QNDPPSLETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLRHKFFQKAKNKEFL
QEKTLQRAPTISERAKKVRRVPGSSGRLHKTEDGGWEWSDDEFDEESEEGKAAISQLRSP
RVKESISNSELFPTTDPVGTLLQVPEQISAHLPQPAGQIATQPTQVSLPPTAEPAKTAQA
LSSGSGSQETKIPISLVLRLRNSKKELNDIRFEFTPGRDTAEGVSQELISAGLVDGRDLV
IVAANLQKIVEEPQSNRSVTFKLASGVEGSDIPDDGKLIGFAQLSIS
|
|
|
|---|
| BDBM50309910 |
|---|
| n/a |
|---|
| Name | BDBM50309910 |
|---|
| Synonyms: | CHEMBL608154 | ML-120B | N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H15ClN4O2 |
|---|
| Mol. Mass. | 366.801 |
|---|
| SMILES | COc1c(Cl)cc2c3ccncc3[nH]c2c1NC(=O)c1cccnc1C |
|---|
| Structure | 
|
|---|
Search and Browse
