| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase VRK2 |
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| Ligand | BDBM50309910 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_774538 (CHEMBL1908755) |
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| Kd | >10000±n/a nM |
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| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase VRK2 |
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| Name: | Serine/threonine-protein kinase VRK2 |
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| Synonyms: | VRK2 | VRK2_HUMAN | Vaccinia-related kinase 2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 58156.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_774538 |
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| Residue: | 508 |
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| Sequence: | MPPKRNEKYKLPIPFPEGKVLDDMEGNQWVLGKKIGSGGFGLIYLAFPTNKPEKDARHVV
KVEYQENGPLFSELKFYQRVAKKDCIKKWIERKQLDYLGIPLFYGSGLTEFKGRSYRFMV
MERLGIDLQKISGQNGTFKKSTVLQLGIRMLDVLEYIHENEYVHGDIKAANLLLGYKNPD
QVYLADYGLSYRYCPNGNHKQYQENPRKGHNGTIEFTSLDAHKGVALSRRSDVEILGYCM
LRWLCGKLPWEQNLKDPVAVQTAKTNLLDELPQSVLKWAPSGSSCCEIAQFLVCAHSLAY
DEKPNYQALKKILNPHGIPLGPLDFSTKGQSINVHTPNSQKVDSQKAATKQVNKAHNRLI
EKKVHSERSAESCATWKVQKEEKLIGLMNNEAAQESTRRRQKYQESQEPLNEVNSFPQKI
SYTQFPNSFYEPHQDFTSPDIFKKSRSPSWYKYTSTVSTGITDLESSTGLWPTISQFTLS
EETNADVYYYRIIIPVLLMLVFLALFFL
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| BDBM50309910 |
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| n/a |
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| Name | BDBM50309910 |
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| Synonyms: | CHEMBL608154 | ML-120B | N-(6-chloro-7-methoxy-9H-pyrido[3,4-b]indol-8-yl)-2-methylnicotinamide |
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| Type | Small organic molecule |
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| Emp. Form. | C19H15ClN4O2 |
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| Mol. Mass. | 366.801 |
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| SMILES | COc1c(Cl)cc2c3ccncc3[nH]c2c1NC(=O)c1cccnc1C |
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| Structure | 
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