Ki Summary new BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetSerine/threonine-protein kinase SRPK3
LigandBDBM50355499
Substrate/Competitorn/a
Meas. Tech.ChEMBL_774558
Kd 6000±n/a nM
Citation Davis MIHunt JPHerrgard SCiceri PWodicka LMPallares GHocker MTreiber DKZarrinkar PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol 29:1046-51 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Serine/threonine-protein kinase SRPK3
Name:Serine/threonine-protein kinase SRPK3
Synonyms:MSSK-1 | Muscle-specific serine kinase 1 | SR-protein-specific kinase 3 | SRSF protein kinase 3 | Serine/arginine-rich protein-specific kinase 3 | Serine/threonine-protein kinase 23
Type:PROTEIN
Mol. Mass.:62021.04
Organism:Homo sapiens (Human)
Description:ChEMBL_655942
Residue:567
Sequence:
MSASTGGGGDSGGSGGSSSSSQASCGPESSGSELALATPVPQMLQGLLGSDDEEQEDPKD
YCKGGYHPVKIGDVFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETA
VDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNY
QGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQA
GAPPPSRSIVSTAPQEVLQTGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAATQ
AEDSGLRLDGGSGSTSSSGCHPGGARAGPSPASSSPAPGGGRSLSAGSQTSGFSGSLFSP
ASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHF
TEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAH
IVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSA
FLLPMMEYIPEKRASAADCLQHPWLNP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50355499
n/a
NameBDBM50355499
Synonyms:CHEMBL1908395 | CHEMBL1908842
TypeSmall organic molecule
Emp. Form.C26H32N6O2
Mol. Mass.460.5713
SMILESCN(C)CC(=O)N1CCC(CC1)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCCCC1 |t:31|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: