| Reaction Details |
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 | Report a problem with these data |
| Target | Cyclin-dependent kinase 16 |
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| Ligand | BDBM24654 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_774513 (CHEMBL1908730) |
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| Kd | 1.1±n/a nM |
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| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cyclin-dependent kinase 16 |
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| Name: | Cyclin-dependent kinase 16 |
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| Synonyms: | CDK16 | CDK16_HUMAN | PCTAIRE1 | PCTK1 | Serine/threonine-protein kinase PCTAIRE-1 |
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| Type: | Protein |
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| Mol. Mass.: | 55721.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q00536 |
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| Residue: | 496 |
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| Sequence: | MDRMKKIKRQLSMTLRGGRGIDKTNGAPEQIGLDESGGGGGSDPGEAPTRAAPGELRSAR
GPLSSAPEIVHEDLKMGSDGESDQASATSSDEVQSPVRVRMRNHPPRKISTEDINKRLSL
PADIRLPEGYLEKLTLNSPIFDKPLSRRLRRVSLSEIGFGKLETYIKLDKLGEGTYATVY
KGKSKLTDNLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIIHTEKSLTLVF
EYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQKVLHRDLKPQNLLINERGEL
KLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYSTQIDMWGVGCIFYEMATGRP
LFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYNYPKYRAEALLSHAPRLDSDGA
DLLTKLLQFEGRNRISAEDAMKHPFFLSLGERIHKLPDTTSIFALKEIQLQKEASLRSSS
MPDSGRPAFRVVDTEF
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| BDBM24654 |
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| n/a |
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| Name | BDBM24654 |
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| Synonyms: | 4-N-(2,6-dichlorobenzene)-3-N-(piperidin-4-yl)-1H-pyrazole-3,4-diamido | AT7519 | JMC514986 Compound 33 | pyrazole diamide, 33 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H17Cl2N5O2 |
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| Mol. Mass. | 382.244 |
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| SMILES | Clc1cccc(Cl)c1C(=O)Nc1cn[nH]c1C(=O)NC1CCNCC1 |
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| Structure | 
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