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TargetSerine/threonine-protein kinase SRPK3
LigandBDBM50355497
Substrate/Competitorn/a
Meas. Tech.ChEMBL_774558
Kd>10000±n/a nM
Citation Davis MIHunt JPHerrgard SCiceri PWodicka LMPallares GHocker MTreiber DKZarrinkar PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol 29:1046-51 (2011) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Serine/threonine-protein kinase SRPK3
Name:Serine/threonine-protein kinase SRPK3
Synonyms:MSSK-1 | Muscle-specific serine kinase 1 | SR-protein-specific kinase 3 | SRSF protein kinase 3 | Serine/arginine-rich protein-specific kinase 3 | Serine/threonine-protein kinase 23
Type:PROTEIN
Mol. Mass.:62021.04
Organism:Homo sapiens (Human)
Description:ChEMBL_655942
Residue:567
Sequence:
MSASTGGGGDSGGSGGSSSSSQASCGPESSGSELALATPVPQMLQGLLGSDDEEQEDPKD
YCKGGYHPVKIGDVFNGRYHVVRKLGWGHFSTVWLCWDIQRKRFVALKVVKSAGHYTETA
VDEIKLLKCVRDSDPSDPKRETIVQLIDDFRISGVNGVHVCMVLEVLGHQLLKWIIKSNY
QGLPVPCVKSIVRQVLHGLDYLHTKCKIIHTDIKPENILLCVGDAYIRRLAAEATEWQQA
GAPPPSRSIVSTAPQEVLQTGKLSKNKRKKMRRKRKQQKRLLEERLRDLQRLEAMEAATQ
AEDSGLRLDGGSGSTSSSGCHPGGARAGPSPASSSPAPGGGRSLSAGSQTSGFSGSLFSP
ASCSILSGSSNQRETGGLLSPSTPFGASNLLVNPLEPQNADKIKIKIADLGNACWVHKHF
TEDIQTRQYRAVEVLIGAEYGPPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAH
IVELLGDIPPAFALSGRYSREFFNRRGELRHIHNLKHWGLYEVLMEKYEWPLEQATQFSA
FLLPMMEYIPEKRASAADCLQHPWLNP
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  Blast E-value cutoff:
BDBM50355497
n/a
NameBDBM50355497
Synonyms:AZD-6244 | CHEMBL1614701
TypeSmall organic molecule
Emp. Form.C17H15BrClFN4O3
Mol. Mass.457.681
SMILESCn1cnc2c(F)c(Nc3ccc(Br)cc3Cl)c(cc12)C(=O)NOCCO
Structure
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