Ki Summary

Reaction Details

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Target

Cyclin-dependent kinase-like 3

Ligand

BDBM4851

Substrate/Competitor

n/a

Meas. Tech.

ChEMBL_774302 (CHEMBL1908519)

>10000±n/a nM

Citation

Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article

More Info.:

Get all data from this article, Assay Method

Cyclin-dependent kinase-like 3

Name:

Cyclin-dependent kinase-like 3

Synonyms:

CDKL3 | CDKL3_HUMAN | NKIAMRE | Serine/threonine-protein kinase NKIAMRE

Type:

PROTEIN

Mol. Mass.:

67544.66

Organism:

Homo sapiens (Human)

Description:

ChEMBL_774302

Residue:

592

Sequence:

MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLP
QVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELK
AKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVRV
IKVKGGRGDISEPKKKEYEGGLGQQDANENVHPMSPDTKLVTIEPPNPINPSTNCNGLKE
NPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVRLTERAKKRRTSSQSIGQVMPNSRQE
DPGPIQSQMEKGIFNERTGHSDQMANENKRKLNFSRSDRKEFHFPELPVTIQSKDTKGME
VKQIKMLKRESKKTESSKIPTLLNVDQNQEKQEGGDGHCEGKNLKRNRFFFW

BDBM4851

n/a

Name

BDBM4851

Synonyms:

(4-chlorophenyl)-[4-(4-pyridylmethyl)phthalazin-1-yl]amine | (A) PTK787 | CGP 79787 | CHEMBL101253 | CHEMBL75232 | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)-1-phthalazinamine | N-(4-chlorophenyl)-4-(pyridin-4-ylmethyl)phthalazin-1-amine | PTK-787 | PTK787 | ZK222584 | cid_151194

Type

Small organic molecule

Emp. Form.

C20H15ClN4

Mol. Mass.

346.813

SMILES

Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1

Structure