| Reaction Details |
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 | Report a problem with these data |
| Target | Calcium/calmodulin-dependent protein kinase kinase 1 |
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| Ligand | BDBM50355495 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_774623 (CHEMBL1908840) |
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| Kd | >10000±n/a nM |
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| Citation |  Davis, MI; Hunt, JP; Herrgard, S; Ciceri, P; Wodicka, LM; Pallares, G; Hocker, M; Treiber, DK; Zarrinkar, PP Comprehensive analysis of kinase inhibitor selectivity. Nat Biotechnol29:1046-51 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Calcium/calmodulin-dependent protein kinase kinase 1 |
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| Name: | Calcium/calmodulin-dependent protein kinase kinase 1 |
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| Synonyms: | CAMKK1 | CAMKKA | CaM-kinase kinase alpha | KKCC1_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 55727.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_774623 |
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| Residue: | 505 |
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| Sequence: | MEGGPAVCCQDPRAELVERVAAIDVTHLEEADGGPEPTRNGVDPPPRARAASVIPGSTSR
LLPARPSLSARKLSLQERPAGSYLEAQAGPYATGPASHISPRAWRRPTIESHHVAISDAE
DCVQLNQYKLQSEIGKGAYGVVRLAYNESEDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQ
AAQGGPAKQLLPLERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVME
VPCDKPFSEEQARLYLRDVILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQF
EGNDAQLSSTAGTPAFMAPEAISDSGQSFSGKALDVWATGVTLYCFVYGKCPFIDDFILA
LHRKIKNEPVVFPEEPEISEELKDLILKMLDKNPETRIGVPDIKLHPWVTKNGEEPLPSE
EEHCSVVEVTEEEVKNSVRLIPSWTTVILVKSMLRKRSFGNPFEPQARREERSMSAPGNL
LVKEGFGEGGKSPELPGVQEDEAAS
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| BDBM50355495 |
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| n/a |
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| Name | BDBM50355495 |
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| Synonyms: | CHEMBL1908391 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H30N6OS |
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| Mol. Mass. | 498.642 |
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| SMILES | CN1CCN(Cc2ccc(cc2)C(=O)Nc2ccc(C)c(Nc3nc(cs3)-c3cccnc3)c2)CC1 |
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| Structure | 
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