| Reaction Details |
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 | Report a problem with these data |
| Target | Lactoylglutathione lyase |
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| Ligand | BDBM50355547 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_776454 (CHEMBL1913551) |
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| IC50 | 2000±n/a nM |
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| Citation |  Takasawa, R; Tao, A; Saeki, K; Shionozaki, N; Tanaka, R; Uchiro, H; Takahashi, S; Yoshimori, A; Tanuma, S Discovery of a new type inhibitor of human glyoxalase I by myricetin-based 4-point pharmacophore. Bioorg Med Chem Lett21:4337-42 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lactoylglutathione lyase |
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| Name: | Lactoylglutathione lyase |
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| Synonyms: | Aldoketomutase | GLO1 | Glx I | Glyoxalase 1 (GLO1) | Glyoxalase I | Ketone-aldehyde mutase | LGUL_HUMAN | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase |
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| Type: | Enzyme |
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| Mol. Mass.: | 20772.95 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q04760 |
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| Residue: | 184 |
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| Sequence: | MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQK
CDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNS
DPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKM
ATLM
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| BDBM50355547 |
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| n/a |
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| Name | BDBM50355547 |
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| Synonyms: | CHEMBL1910548 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H15NO3S |
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| Mol. Mass. | 325.382 |
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| SMILES | COc1ccc(\C=C(\CC(O)=O)c2nc3ccccc3s2)cc1 |
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| Structure | 
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