| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Lactoylglutathione lyase |
|---|
| Ligand | BDBM62042 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_776454 (CHEMBL1913551) |
|---|
| IC50 | 93200±n/a nM |
|---|
| Citation |  Takasawa, R; Tao, A; Saeki, K; Shionozaki, N; Tanaka, R; Uchiro, H; Takahashi, S; Yoshimori, A; Tanuma, S Discovery of a new type inhibitor of human glyoxalase I by myricetin-based 4-point pharmacophore. Bioorg Med Chem Lett21:4337-42 (2011) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Lactoylglutathione lyase |
|---|
| Name: | Lactoylglutathione lyase |
|---|
| Synonyms: | Aldoketomutase | GLO1 | Glx I | Glyoxalase 1 (GLO1) | Glyoxalase I | Ketone-aldehyde mutase | LGUL_HUMAN | Methylglyoxalase | S-D-lactoylglutathione methylglyoxal lyase |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 20772.95 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q04760 |
|---|
| Residue: | 184 |
|---|
| Sequence: | MAEPQPPSGGLTDEAALSCCSDADPSTKDFLLQQTMLRVKDPKKSLDFYTRVLGMTLIQK
CDFPIMKFSLYFLAYEDKNDIPKEKDEKIAWALSRKATLELTHNWGTEDDETQSYHNGNS
DPRGFGHIGIAVPDVYSACKRFEELGVKFVKKPDDGKMKGLAFIQDPDGYWIEILNPNKM
ATLM
|
|
|
|---|
| BDBM62042 |
|---|
| n/a |
|---|
| Name | BDBM62042 |
|---|
| Synonyms: | 2-(p-anisoylamino)benzoic acid | 2-[(4-methoxybenzoyl)amino]benzoic acid | 2-[(4-methoxyphenyl)carbonylamino]benzoic acid | 2-[[(4-methoxyphenyl)-oxomethyl]amino]benzoic acid | KSC-20-006 | KUC106458N | cid_721421 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H13NO4 |
|---|
| Mol. Mass. | 271.268 |
|---|
| SMILES | COc1ccc(cc1)C(=O)Nc1ccccc1C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
